This impressive white marble building was built between 1515 and 1560 to house a charitable society dedicated to San Rocco.
Soon after its completion, the great 16th-century Venetian artist Tintoretto won the competition to paint a central panel for the ceiling of the Sala dell'Albergo by entering the building and putting his painting in its intended place before the judging, much to the irritation of his rival artists.
He later decorated its walls and ceilings with a complete cycle of paintings, which are considered to be the artist's masterpiece. The earliest works, in the Sala dell'Albergo, date to 1564 and 1576 and include The Glorification of St. Roch, Christ before Pilate, the Ecce Homo, and the most powerful of all, The Crucifixion.
