Lyon stands on the site of the ancient Roman city called Lugdunum, founded in 43 BC, which was the capital of Gaul. This superb archaeology museum displays Gallo-Roman-era objects including vases, gravestones, mosaics, statues, coins, and ceramics. 

The antiquities displayed are from onsite digs (from the city of Lugdunum) as well as nearby Roman archaeological sites of Saint-Romain-en-Gal and Vienne. 

The collection is renowned for its breadth and variety. Highlights of the collection include a monumental Hercules sculpture, decorative marble work from ancient baths, and a magnificent 100-square-meter floor mosaic depicting images related to the God of Oceans.

The museum also extends to the archaeology site that is nearby, about 300 meters from the museum. This site boasts the oldest ancient ruins in France, including two Roman theaters. The Grand Théâtre dating back to 15 BC was where tragedies and comedies were performed. The Odéon was the theater for musical performances. There are also the foundations of a temple that was devoted to the Goddess Cybele.