In 1349, the workers responsible for the maintenance of the cathedral created Maison de l'Oeuvre Notre-Dame. The east wing of the building is the oldest part (it was renovated in the 16th century), and the west wing was built from 1579 to 1585.

The building houses the Musee du Notre-Dame, which houses the finest collections of medieval European art. The collection represents seven centuries of art created in Strasbourg and the Upper Rhine region.

  On display are the origins of the sculpture of the cathedral as well as paintings and stained glass windows. Visitors should make sure to see the window "Tête de Christ" in Wissembourg, one of the oldest known stained glass windows